PeptiGrowth Inc.

<span>PG-002</span>TGFβ1 Inhibitor (TGFβ1 Binding Peptide)

PG-002TGFβ1 Inhibitor (TGFβ1 Binding Peptide)

Small molecule inhibitors “kinase inhibitors” have problems on its specificity and its necessity to act in cells, and in addition, neutralizing antibodies are costly and also difficult to prove animal-free.
Our PG-002 is a special peptide that binds TGFβ1 ligand outside the cell and exerts inhibitory activity.
Since it is produced by complete chemical synthesis, we are able to provide animal-free certification.

Method for Inhibiting TGFβ1 Signal

Method for Inhibiting TGFβ1 Signal 1
Method for Inhibiting TGFβ1 Signal 2
Method for Inhibiting TGFβ1 Signal 3

*This is for illustrative purpose.

Equivalent Inhibitory Activity to TGFβ-Neutralizing Antibody

The inhibitory activity against TGFβ1 was measured by SBE Reporter Assay, and PG-002 showed 100% inhibitory activity at 10nM against 0.13nM TGFβ1 (right figure). Using the panel assay, we also confirmed that it does not inhibit other signaling pathways.

Inhibition Curve against TGFβ1

Sample Requests and Purchases of Our Products

We offer our products worldwide through the following distributors. Please contact the relevant distributors depending on your region.

Please note that currently, we offer all products except PG-009 through distributors. For inquiries regarding PG-009 and bulk orders, please contact us directly through the inquiry form on our website.

Distributer

Scientist.com https://app.scientist.com/inventory?query=PeptiGrowth&commit=Next
Stratech https://www.stratech.co.uk/
Tebubio https://www.tebubio.com/search?q=PeptiGrowth
Genesee Scientific https://geneseesci.com/
Abacus dx https://www.abacusdx.com/