Small molecule inhibitors “kinase inhibitors” have problems on its specificity and its necessity to act in cells, and in addition, neutralizing antibodies are costly and also difficult to prove animal-free.
Our PG-002 is a special peptide that binds TGFβ1 ligand outside the cell and exerts inhibitory activity.
Since it is produced by complete chemical synthesis, we are able to provide animal-free certification.
*This is for illustrative purpose.
The inhibitory activity against TGFβ1 was measured by SBE Reporter Assay, and PG-002 showed 100% inhibitory activity at 10nM against 0.13nM TGFβ1 (right figure). Using the panel assay, we also confirmed that it does not inhibit other signaling pathways.
Stability Data in Serum Free Medium at 37℃
(To be obtained soon) Residual Property data
| Formulation | Lyophilized |
|---|---|
| Storage Condition | ≦-20℃ |
| Purity | ≧95% (HPLC) |
| Molecular Weight | 2587.90 (Acetate) |
| Product Size | 10µg, 100µg per a glass vial |
We offer our products worldwide through the following distributors. Please contact the relevant distributors depending on your region. Please note that currently, we offer all products except PG-009 through distributors. For inquiries regarding PG-009 and bulk orders, please contact us directly through the inquiry form on our website.
Additionally, we provide 1 free sample per product to each organization/lab for our products currently on the market. Please fill out the Sample Request Form to request free samples.
PeptiGrowth Inc.
Nihonbashi Life Science Building 7, 9-10, Nihonbashi Horidomecho 1-chome, Chuo-ku, Tokyo 103-0012, Japan
TEL +81-70-7789-3905