Novel functional peptides capable of separately inhibiting the BMP4 family and BMP7 family.
PG-005 and PG-006 are special peptides that are fully chemically synthesized and possess selective inhibitory activity against the BMP7 family and BMP4 family, respectively. They make it possible to separately inhibit the BMP4/7 families, which was impossible with existing small kinase inhibitors or Noggin, and can be utilized for detailed analysis and control of BMP signaling, as well as for constructing new cellular differentiation pathways.
Binding to the BMP4 family or BMP7 family and inhibiting their signals separately.
*This is for illustrative purpose.