PG-007VEGF Alternative Peptide (VEGFR2 agonist)

Fully-Chemically Synthesized Peptide with
Similar Functionality to VEGF

PG-007 has a similar function to VEGF (Vascular endothelial growth factor) and can be used to promote the proliferation of endothelial cells and induce the differentiation of iPS cells into vascular endothelial cells.

PG-007 exhibits selective binding affinity to VEGFR2 and agonist activity.

VEGF Alternative Peptide (VEGFR2 agonist)

*This is for illustrative purpose.

PG-007 has been confirmed to possess phosphorylation capability on VEGFR2 similar to VEGF, as well as the ability to promote proliferation of iPSC-derived endothelial cells.

VEGFR2 phosphorylation (phospho-RTK array)

Proliferation of iPSC-derived endothelial cell

Stability Data ＆ Safety Data

Stability Data in Serum Free Medium at 37℃
(To be obtained soon) Residual Property data

Application Note

We demonstrated the differentiation of iPSCs into NKT cells through differentiation into hematopoietic stem and progenitor cells (HSPCs) using PG-007, PG-008, and PG-010, and compared the productivity of HSPCs and NKT cells and the functionality of NKT cells with the control condition using VEGF, CHIR99021 (Wnt3a agonist), and TPO.

PG-peptides

Control

Microscopic observation on differentiation process of iPSCs into HSPCs at Day 9
Detailed application note is available HERE
Whitepaper is available HERE

PG-007 Product Overview

Formulation	Lyophilized
Storage Condition	≦-20℃
Purity	≧95% (HPLC)
Molecular Weight	4785.32
Product Size	5 µg (equivalent to rVEGF 40 µg) 50 µg (equivalent to rVEGF 400 µg) 500 µg (equivalent to rVEGF 4 mg)

Information sheet

Sample Requests and Purchases of Our Products

We offer our products worldwide through the following distributors. Please contact the relevant distributors depending on your region. Please note that currently, we offer all products except PG-009 through distributors. For inquiries regarding PG-009 and bulk orders, please contact us directly through the inquiry form on our website.

Additionally, we provide 1 free sample per product to each organization/lab for our products currently on the market. Please fill out the Sample Request Form to request free samples.

Distributor

Scientist.com	https://app.scientist.com/inventory?q=&filters%5Bmanufacturer_name%5D%5B%5D=PeptiGrowth&filters%5Binventory_config_uuid%5D%5B%5D=b2c86b9f-e0eb-48b3-b138-66161a43f02c
Stratech	https://www.stratech.co.uk/
Genesee Scientific	https://geneseesci.com/
Abacus dx	https://www.abacusdx.com/
Labscoop	https://labscoop.com/us/en
Thomas Scientific	https://www.thomassci.com/browse-by/suppliers/peptigrowth